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Customer scenarios

Hilary

18-year-old Hilary has been using Histahive for the past week and has already found a reduction in her symptoms. However, she is wondering what self-care advice you can offer to help her symptoms and prevent worsening.

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Hilary should try wearing loose, smooth-textured cotton clothing to prevent friction against the wheals.

She should avoid using harsh, fragranced products, including soap and lotions, on her skin as they can cause irritation.

She should protect her skin from the sun by applying sunscreen liberally; however, she should choose a product that is suitable for sensitive skin.

She should cool her skin – cool showers and baths can help to relieve the itching and burning sensation. Hilary could also use a cold washcloth or ice cube over the sore area.

She should track her symptoms – although CIU has no obvious cause, Hilary may be able to identify potential aggravating triggers by keeping a diary of daily foods, etc to see if there are potential trends associated with her flare ups.


Henry

45-year-old Henry has come into the pharmacy to purchase Histahive for his wife. He tells you that she has been taking it “for 6 months”, as advised by her HCP, but her symptoms aren’t getting better. In fact, the wheals have spread and become more painful. He tells you that he has seen a big change in her mood and that she “isn’t quite herself and avoids going out”. Consider what you would do in this instance.

Select your answers from the options below.

1.

Sell Histahive as requested and tell them to carry on as normal

INCORRECT! Henry’s wife has shown red flag symptoms.

2.

Refer Henry’s wife to her HCP to seek further guidance

CORRECT! Henry’s wife has shown red flag symptoms. Her HCP may need to investigate further or change her treatment plan.

3.

Offer self-care advice to help manage her symptoms

CORRECT! You can always support your customers by offering self-care advice and by being empathetic to this distressing condition.

REVEAL ANSWERS

References

1. AllergyUK. Your quick quide to: Chronic Spontaneous Urticaria (CSU). 2021.
Available at: https://www.allergyuk.org/wp-content/uploads/2024/09/Chronic-Spontaneous-Urticaria-v2.pdf

2. Bartlett D, et al. DermNet. Chronic spontaneous urticaria. 2019. Available at: https://dermnetnz.org/topics/chronic-spontaneous-urticaria

3. Brind'Amour.K et al. All about common skin disorders. Healthline. 2024. Available at: https://www.healthline.com/health/skin-disorders#list

4. NHS. Shingles. 2023. Available at: https://www.nhs.uk/conditions/shingles/

5. SmPC. Histahive 180mg film-coated tablets. 2025. Available at: https://www.medicines.org.uk/emc/product/100389/smpc

6. Craun KL, et al. Fexofenadine. 2024. Available at: https://www.ncbi.nlm.nih.gov/books/NBK556104/

7. Cafasso J. Anticholinergics. 2024. Available at: https://www.healthline.com/health/anticholinergics#side-effects

8. Gómez RM, et al. Update meta-analysis on the efficacy and safety issues of fexofenadine. World Allergy Organ J. 2023. doi: 10.1016

9. Mayo Clinic. Chronic Hives. 2024. Available at: https://www.mayoclinic.org/diseases-conditions/chronic-hives/diagnosis-treatment/drc-20352723#:~:text=The%20following%20self-care%20tips%20may%20help%20you%20manage,the%20sun.%20...%208%20Track%20your%20symptoms.

Online references last accessed May 2025.

Product information

Product Name: Histahive 180mg Film-Coated Tablets. Active ingredient: Fexofenadine Hydrochloride. Each film-coated tablet contains 180 mg of fexofenadine hydrochloride, which is equivalent to 168 mg of fexofenadine. Product License number: PL 08553/0756. Name and address of the product licence holder: Dr. Reddy’s Laboratories (UK) Ltd. 410 Cambridge Science Park, Milton Road, Cambridge, CB40PE. Supply Classification: P Product. Indication: indicated in adults and children 12 years and older for the relief of symptoms associated with chronic idiopathic urticaria. Side Effects: The following side effects have also been reported: Common side effects (may affect up to 1 in 10 people): headache, drowsiness, feeling sick (nausea), dizziness. Uncommon side effects (may affect up to 1 in 100 people): tiredness, sleepiness. If you get any side effects talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. Refer to product SmPC for complete information Contraindications: Hypersensitivity to the active substance or to any of the excipients. You should contact your doctor immediately if you have symptoms of a serious allergic reaction such as swelling of the face, lips, tongue or throat and difficulty breathing after taking the tablets Warnings and Precautions: Talk to your doctor or pharmacist before taking Histahive if you have problems with your liver or kidneys, if you have or ever had heart problems, as fexofenadine, like other antihistamines may cause your heart to beat faster (tachycardia) or you feel your heart beating (palpitations), or if you are elderly. If any of these apply to you, or if you are not sure, tell your doctor or pharmacist before taking Histahive. Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. This is especially important for the following medicines: Erythromycin (an antibiotic) Ketoconazole (a treatment for fungal infections) If you are taking apalutamide (a medicine to treat prostate cancer), as the effect of fexofenadine may be decreased. Indigestion remedies containing aluminium and magnesium may affect the action of Histahive, by lowering the amount of medicinal product absorbed. It is recommended that you leave about 2 hours between the time that you take Histahive and your indigestion remedy. If you are pregnant or breastfeeding, think you may be pregnant or planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. Histahive should not be taken during pregnancy and whilst breast-feeding unless advised by a doctor. Histahive is unlikely to affect your ability to drive or operate machinery. However, you should check that these tablets do not make you feel sleepy or dizzy before driving or operating machinery. Histahive contains Allura Red AC Lake, which may cause allergic reactions. Dosage and Method of Use: The recommended dose is one tablet (180mg) daily. Take your tablet with water before a meal. Cost: RRP (ex VAT) 10 tablets pack: £4.58 30 tablets pack: £10.83. Further Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: https://www.medicines.org.uk/emc/product/100389/smpc#about-medicine.

Adverse events should be reported. Reporting forms and information can be found at yellowcard.mhra.gov.uk.

Adverse events should also be reported to Pharmacovigilance at Dr Reddy’s via DrreddysGB@EU.Propharmagroup.com.

Date: Essential Information is prepared on 25 November 2024 of Histahive 180mg Film-Coated Tablets

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