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Drug Safety Update

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MHRA warns of risk of overuse of SABA in asthma

Warning of risk of severe asthma attacks and increased mortality associated with overuse of short-acting SABA in patients with asthma.

29 Apr 2025

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Montelukast PIL updated to warn of neuropsychiatric reactions

MHRA says patients should be alert to behaviour and mood-related changes associated with the treatment, and seek urgent medical attention if neuropsychiatric reactions occur.

30 Apr 2024

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New prescribing rules for isotretinoin address safety concerns

Treatment with isotretinoin for patients under 18 must now be approved by two prescribers, under new MHRA rules.

31 Oct 2023

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MHRA reminder of risks of taking NSAIDs in late pregnancy

Reminder that the use of systemic NSAIDs is contraindicated in the last trimester of pregnancy (after 28 weeks of pregnancy)

27 Jun 2023

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Erythromycin alert for patients with prolonged QT interval

Potential drug interaction between rivaroxaban and erythromycin resulting in increased risk of bleeding identified

21 Dec 2020

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