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Clinical

Once-promising Covid drug has ‘little to no survival impact’

Remdesivir – hailed in May as a potential breakthrough – has little impact on survival rates for patients hospitalised with the virus, says WHO.

Elevated INR seen in patients on anticoagulants during pandemic

MHRA warns that acute illness may exaggerate effect of warfarin tablets and necessitate dose reduction.

R number falling suggests latest data from REACT-1 coronavirus study

Study indicates R number could have fallen from 1.47  between 20 August to 26 September to around 1.06.

Over-50s suffering with loneliness at risk of diabetes

KCL study shows a strong relationship between loneliness and the later onset of type 2 diabetes

Discovery of four Covid-19 risk groups could help guide treatment

A risk identification tool uses the groupings to help clinical staff choose the best course of treatment for patients.

‘Immediate NHS action’ to safeguard hydrocortisone after Covid study

Seriously ill coronavirus patients have a better than 90 per cent chance of improved recovery when given a seven-day course of hydrocortisone.

Children with gastro problems should be tested for Covid-19

Researchers have called for children with gastrointestinal symptoms to be tested for Covid-19.

Clozapine toxicity in spotlight after two Coroners reports

Monitoring blood concentrations of clozapine for toxicity is now advised in certain clinical situations says MHRA.

Hypertension treatments could improve Covid survival rates

People with high blood pressure have a better chance of surviving Covid-19 if they are taking hypertension medications, research shows. 

Bipolar disorder tablets to be discontinued

Priadel 200mg and 400mg modified release tablets are to be discontinued, with all remaining supplies expected to run out by April of next year. 

Value of statins in the elderly confirmed

Starting statins reduces the risk of all-cause and cardiovascular mortality among people aged 75 years and older, a new study finds. 

Covid infection rates were falling in early July

REACT-1 study results give snapshot of Covid situation in late June and early July as lockdown started to ease.

Benefits of steroids in inhalers outweighs risk say researchers

The advantages of using inhalers and nebulisers containing steroids outweigh the risks, claim researchers.   

Study to look at long term impacts of Covid-19

The study's findings will support the development of strategies for clinical and rehabilitation care

Most vulnerable children no longer need to shield

Independent evidence from RCPCH shows the risk of serious illness for children and young people is low.

Coeliac 'can be diagnosed with just a blood test'

Coeliac can be diagnosed in some adults with just a blood test, says the British Society of Gastroenterology.

Remdesivir gets EU approval as Trump hoovers up supplies

The European Commission granted a conditional marketing authorisation for the drug earlier today

NICE recommends steam treatment for enlarged prostate

Rezum recommended as a treatment option for moderate to severe lower urinary tract symptoms.

HIV drug has ‘no benefit’ in Covid-19 patients

The HIV medicine lopinavir-ritonavir has “no beneficial effect” in patients hospitalised with Covid-19, Oxford researchers have said.

Covid-19 prevention trial given green light to recruit more subjects

The MHRA has approved the recruitment of further participants for an Oxford trial investigating the use of hydroxychloroquine to prevent Covid-19.

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