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Antibacterials (also referred to as antibiotics and antimicrobials) have revolutionised medical care, enabling a wide range of infections to be treated and lives saved. However, the inappropriate and excessive use of antibacterials, together with a reduction in the rate of new antibacterial development, has led to the growth of resistant strains or superbugs.

Bacterial resistance is increasingly becoming an issue for the management of infection. There are several mechanisms for developing resistance, so previously active antibacterials may have little or no effect on a bacterium.

Resistant organisms are on the rise and new multi-resistant mechanisms continue to be identified. Experts are finding ways to control organisms like MRSA, but others are of increasing concern.