H2-antagonists

Famotidine and ranitidine are H2-antagonists, which can be used if antacids and alginates are not helping to reduce the symptoms of indigestion and heartburn. They work by inhibiting the production of acid in the stomach lining. They give up to 12 hours' relief, but should only be used for a few days. If symptoms have not improved by this time, refer customers to the pharmacist. H2-antagonists should not be used during pregnancy or while breastfeeding without medical advice. Examples: PepcidTwo, Zantac 75 Relief.

Proton pump inhibitors (PPIs)

Proton pump inhibitors (e.g. omeprazole, pantoprazole, esomeprazole) work by inhibiting the production of stomach acid. They don't provide rapid relief in the same way that other indigestion remedies do, which needs to be explained to customers.

PPIs start to suppress acid production within one to two hours of taking the first dose and build to a maximum effect after two to four days. PPIs are intended for shortterm use. Once symptoms have been completely relieved, treatment should be stopped. Examples: Zanprol Tablets, Pantoloc Control.

Following a P to GSL switch, esomeprazole is available as Nexium Control.

What forms are available?

Some indigestion and heartburn products are available as liquids and tablets. Liquid forms may have a faster action, whereas tablets may be more convenient. It is important to match the appropriate product and form to your customer's needs.